PLENARY 5: Immune System and Migraine

Saturday, June 15, 2024
2:15 PM - 3:15 PM
Grand Ballroom 5-9

Details

2:15 pm – 2:25 pm: Introductions: The Clinical Tie-In of the Immune System 2:25 pm – 2:45 pm: Mast Cells 2:45 pm – 3:05 pm: Regulatory T cells (Tregs) and Cytokines 3:05 pm – 3:15 pm: Panel Discussion


Speaker

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Anne Yacoub
Assistant Professor Of Neurology, Co-director Johns Hopkins Headache Center
Johns Hopkins

Introductions: The Clinical Tie-In of the Immune System

2:15 PM - 2:25 PM

Anne Damian Yacoub, MD is an Assistant Professor of Neurology at Johns Hopkins and serves as co-director of the Johns Hopkins headache center. She is fellowship trained in both headache medicine and neuroimmunology. She earned her medical degree at the University of Arizona College of Medicine, followed by residency in Neurology at the McGill University Health Center/ Montreal Neurological Institute. She spent a year in Chicago as the Seymour Diamond Headache fellow, followed by a subsequent fellowship at Johns Hopkins studying neuroimmunology and neurological infections, after which she joined the Neurology faculty at Johns Hopkins.
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Dan Levy
Harvard Medical School/BIDMC

Mast Cells

2:25 PM - 2:45 PM

Dr. Dan Levy is an Associate Professor of Anesthesia at Harvard Medical School and a Principal Investigator of the basic Headache and Pain research lab in the Department of Anesthesia, Critical Care and Pain Medicine at the Beth Israel Deaconess Medical Centre (BIDMC). Dr. Levy received his Ph.D. in Neuroscience from the University of Calgary. Dr. Levy’s research seeks to define neural, glial, and immune mechanisms underlying the development of headaches, such as migraines - vital information required to develop novel evidence-based therapeutic approaches. To better understand the triggering mechanism of migraine, Dr. Levy studies the trigeminal meningeal sensory system - the neuronal population whose activation and sensitization have been most directly implicated in the genesis of migraine headaches. The responses of meningeal sensory afferents are assessed in health and under migraine-like conditions in rodent models using in-vivo electrophysiology in anesthetized animals and two-photon calcium imaging in behaving animals. Dr. Levy’s studies are primarily sponsored by the National Institutes of Health (NIH/NINDS).
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Yu-Qing Cao
Washington University In St. Louis School of Medicine

Regulatory T cells (Tregs) and Cytokines

2:45 PM - 3:05 PM

Dr. Yu-Qing Cao is an associate professor in the Department of Anesthesiology and Pain Center of Washington University in St. Louis School of Medicine. Her lab studies how ion channels, neuropeptides and neuro-immune interactions contribute to the pathophysiology of chronic migraine and post-traumatic headache. Through these mechanistic studies, novel molecular and cellular targets can be identified for the development of new therapeutics for migraine and other chronic headache disorders.

Moderators

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William Renthal
Brigham And Women's Hospital / Harvard Medical School

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